Entries Tagged 'Gene Therapy' ↓

Advantage And Disadvantages Of Using Adenoviral Vector In Gene Therapy

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Advantages Of Adenoviral Vector:

  • They can replicate independent of host cell division.
  • They have the capacity to transducer a a board range of human tissues like hepatocytes, cardiac and skeletal muscles vascular endothelium etc.

How Can A Therapeutic Gene Be Transferred To A Target Tissue

Gene therapy is the most sophisticated forms of treatment for genetic diseases , here the protein the deficiency of which is responsible for the diseases-is not delivered to the body, but the gene itself is delivered. A selected rDNA is introduced into the tissues and the biologically active proteins can be synthesized within the cells. The first clinically trial of gene therapy was for adenosine deaminase (ADA) deficient severe combined immune deficiency(SCID). Continue reading →